Vyvanse dopamine depletion reddit. Personally, I have no experience with methylphenidate.

Vyvanse dopamine depletion reddit But I’ve also read (on Reddit) that regularly taking l-tyrosine with Vyvanse can cause a faster tolerance to Vyvanse. So it is quite well known that microdosing adderall can upregulate dopamine receptors causing a myriad of different problems. What you are describing is a sense of novelty. I wasn't able to tolerate a high enough dose of vyvanse. When the vyvanse first kicks in, I smoke a full cigarette. Like sure, by the evening all my symptoms have gradually come back, but it isn’t like Adderall where it somehow feels like I get 2x ADHD when it wears off. 20mg gives me cry myself to sleep leg cramps. But I couldn’t find anything relating to combining Tongkat Ali w/ Adderall and Is tolerance to Vyvanse (Lisdexamfetamine) (A good example would be precursor depletion) Now while I do take other supplements to assist with Dopamine receptor up-regulation, ever since adding Namenda to my regimen I noticed a distinct increase in amphetamine potency. Discover the science behind Vyvanse, its medical uses, and the implications for individuals seeking treatment. But more, this article talks about what vitamins your body needs to make dopamine - the thing we are really after! (The amino acid tyrosine is first turned into L-dopa, which is then made into dopamine. The role [] I would try taking L-Tyrosine to boost your natural dopamine receptors. I’ve been off it for 2 months and it’s rough but trust me your brain isn’t fried, it will just take time. Was out for a couple weeks but tried other nootropics then and had days off throughout. Parkinson’s and depression however are dopamine deficiency related. It affects various brain regions, including the striatum and the prefrontal cortex, but may not have as pronounced an effect on the prefrontal cortex as Focalin. I’ve always been pretty sure it was the Vyvanse but never heard anyone else having the same experience!! I do on vyvanse. That being said, I feel a lot different on the generic version of Vyvanse I just started taking than I do on Vyvanse brand name. Stay very hydrated and around an hour before you'd start to experience the crash take 1000mg of tyrosine. L-tyrosine plays an important role in dopamine, and it’s had me wondering if I’m not getting enough l-tyrosine as it is & that’s maybe why it helps me. Increasing dopamine without increasing norepinephrine is difficult because norepinephrine is synthesised from dopamine. When people talk about "dopamine depletion" in the context of therapeutic stimulant treatment, what they're actually thinking of is temporary counter-regulatory changes in response to the drug. I’m back at 20mg Vyvanse and the crash isn’t nearly as noticeable. Perhaps it has something to do with the fact that we are running low dopamine and norepinephrine and eating something sugary will help with the sudden depletion. 20 votes, 49 comments. Vyvanse is a powder in gelatin capsule whereas Adderall IR is a tablet and Adderall XR are beads in a gelatin capsule. I am prescribed vyvanse and take it quite often (though not daily) for school and general focus I take lisdexamfetamine (Vyvanse) 40 mg and brexpiprazole (Rexulti) 0. Some individuals might experience increased alertness, improved concentration, and reduced impulsivity. I (21F) have been taking Vyvanse 50mg for 6-7 months now (tried Concerta and Vyvanse 30mg before, but they weren’t quite right for me). CRAVE it. It increases the connections in your neurons and stimulates Aug 7, 2023 · Vyvanse’s effects on dopamine can lead to both positive outcomes and potential side effects. , The amount of insane things I do to seek dopamine is just hurting me on the inside. Prescription drugs known to elevate dopamine are mostly ADHD medication - Ritalin/Concerta, and Adderall/Vyvanse. I could barely get out of bed before and now I just CAN'T be in bed when the effect Context: So I'm ADD and take Vyvanse for it. Vyvanse feels so much more natural, and at least for me, it doesn’t have the same crash that Adderall does. I utilize Wellbutrin for this purpose. Knowing that tyrosine is a amino-precusor of dopamine, supplementing it may result in higher number of dopamine. This is my 6th day on Vyvanse (first ever adhd medication) I’ve found that if I start my day right the momentum continues. Due to this lack of dopamine, people with ADHD are "chemically wired" to seek more etc. Also, I started taking L-theanine at the same time as my adderall and then N-Acetyl-L-Tyrosine (NALT) about 4 hrs after my first dose of adderall and those two supplements have really helped to “take the edge off” of the adderall, significantly reducing the anxiety and general “husk of a human” feeling from taking too many stims and as well as neurotoxicity from dopamine depletion. 15 votes, 41 comments. . I wasn’t ever treated for depression, but taking Vyvanse makes me feel like myself. It never lasted all day for me, and neither did Adderall "XR. I realise that this question may have been asked before multiple times. 5 mg and it’s the best dopamine modulating combo I’ve found for my combination of executive dysfunction and predisposition to depressive symptoms (I have a long history of Honestly I am upset it took me so long to get here. Too much dopamine has the opposite effect: we focus intensely but have trouble task switching or prioritising what to focus on (hyperfocus). To answer this, we need to analyze Vyvanse’s effects on dopamine in detail and compare them to traditional dopamine agonists. Restoration of normal dopamine levels, then, could possibly improve those symptoms. 3-4 beers on the weekend. Also a strong inhibitor. I found while I waited for my doc to send in a new script for the lower dose that if you eat something with lots of protein at the start of the crash, it’s not as bad. But, the rest of the day, I only take 4 or 5 drags and put it out. I've heard some people get different results from dexamphetamine than amphetamine (adderall is a mix of both). Just an fyi. I just switched from Vyvanse to Dex after another year on Vyvanse, and I like it a lot better. This can give them undesirable side effects. if you take it 5 hours before bed you’ll have probably drank some water around the time and the vyvanse isn’t getting an insane dopamine . Side effects will likely be exacerbated, and the crash will be that much worse. Aug 4, 2022 · I'm prescribed 70mg of vyvanse a day in a split dose 40mg/30mg. Various forms of amphetamines like vyvanse, adderall XR, adderall IR. I know this from personal experience with Methylphenidate(zero serotonin activity) I'm focused, alert able to absorb information I need but you won't see me telling you I feel alright, meh I'm okay just don't disturb me :D (no increased sense of well being) This can lead to not only tiredness, but also ADHD-like symptoms, and even loss of sex drive - as dopamine signaling is involved in sexual desire. Both drugs are actually pretty weak when it comes to binding to dopamine receptors and DAT (dopamine transport system) and Paxil is selective - it's affinity is limited to the DAT and D2 receptor the latter actually weakens amphetamine. But this article was retracted so I would take that info with a grain of salt. With Vyvanse, I think alot of the trouble comes from sleep deprivation. It stimulates both dopamine and norepinephrine in your brain. That logic ,taken with its simplicity , would suggest that vyvanse promote the limiting of the effectiveness of itself before its complete excretion. I’ve read that Tongkat Ali can produce insomnia for some users. It acts on dopamine mainly but also serotonin weakly. Thats very interesting. nlm. That it gives you a good natural boost of energy and focus and attention. This is a support group to help with impulsive behaviour towards Eating, Gaming, Gambling, Thrill, and Tech. We recommend browsing /r/adhd on desktop for the best experience. So I can understand. I did some research and found out that vyvanse and other stimulants can cause a depletion of magnesium and potassium, both of which can cause muscle tightness and pain, along with other symptoms I can relate to. In terms of Omega 3 Fish Oil, it may be better for you to have a Fish Oil supplement higher in DHA rather than EPA ; I started on Vyvanse 30mg about a week ago. consider lowering your dosage and taking vitamin c, as well as increasing how much water you drink. Crash eliminated, entirely. I didn't realize how much I rely on vyvanse for motivation, wakefulness, and improved I’ve noticed my vyvanse doesn’t seem to work as well the day after a night of drinking. for your personal case: in all likelihood for your personal case, your dosage is probably too high, and you have a vitamin c deficiency. I was wondering if vyvanse could have the same effect because to me it feels like it? The context needed is given below. Expand user menu Open settings menu. I think it has a lot to do with dopamine burnout to the point that I don't feel joy in much of anything anymore. For folks who are really interested in this, there are some comments like this one with additional info about how alcohol relates with other neurotransmitters, too. My life was a horrendous slow motion car crash before I was put on Vyvanse after a diagnoses (which I thought was going to be dementia) of ADHD at the age I have had severe anxiety since childhood, and I literally don’t remember there was time i was calm and happy, I always was anxious,terrified,depressed and scared of everything but maaaan, Prozac changed my life. Not with alcohol, but since starting vyvanse, I have cut waayyyy down on cigarettes. Since I’ve had enough time to get a better handle on things with what I think is the right dosage for me, I thought I should share my experiences with how Vyvanse affects me, and what are some of the things that I do that affect the way the Omg thank god it’s not just me!!! Sometimes I would think about it and wonder if it was the Vyvanse or if I was developing some sort of sex/porn addiction🫠. Does anyone take Vyvanse and then within the first four hours or something like that hyper focus so much and feel so much dopamine and then it’s like you over worked your brain and then your mood drops? Like it’ll kick in and I’ll do so much or write so much and then it’s like my hyper focusing killied my dopamine reward feeling and mood. When I started on vyvanse, I didn't crave alcohol, or food, or anything. For me caffeine only made my anxiety worse. Vyvanse is prescibed for my friend who just sell the bottles and Ritalin is what im currently prescibed and take so they are not fake or anything. So if you’re thinking of adhd, that isn’t a dopamine deficiency, it’s an issue with the use of dopamine. Is Vyvanse Considered a Dopamine Agonist? Given Vyvanse’s complex mechanism of action, it’s natural to question whether it should be classified as a dopamine agonist. I would take the supplements everyday (mostly the same ones as in your picture) I also take p5p which helps with dopamine. Dilated pupils means your brain is in that mode. Even switching between Dexedrine/Vyvanse and Adderall, which are 75 percent identical in their active ingredients and similar enough in the other 25, works for many. Does anyone have any reliable information on this? Please share any insights. In that sense skipping two doses a week is much easier on your brain and your mental stability/ ability to do life than having to go off your meds an entire month and experience extra low dopamine and extra you could try taking thc or cbd to “take the edge off” but i wouldnt start relying on it. ncbi. The thing about Parkinson's is that it is a disease caused by deficiency in the dopamine system, so it's hard to separate the cause and effect here. nih. Similar situation here. Then I quickly started experiencing the 3pm crash, 6hrs after I take my med. Vyvanse has some slight appetite suppression, but at least I manage to get in a meal a day because my brain is cooperative on Vyvanse. Low dopamine levels are linked with certain health conditions like Parkinson’s disease or depression. I haven't experienced depression at all on Vyvanse and I have been taking it for almost a year. if you are just now noticing these effects for the first time, id take it into consideration that this might just be a part of the depletion of dopamine receptors caused by amphetamines. I am worried by the reports that long-term prescription stimulant use can cause downregulation of dopamine receptors. I thought vyvanse wasn’t for me I thought I wasn’t ever going to find “my” combo but this is it. It may also make you more You can read about the stimulant neurotoxicity there. I'm dreadful with it now. Long-term supplementation with 5-HTP, the immediate precursor of serotonin, can cause dopamine depletion, which may worsen certain neurological and psychiatric diseases . Dose works great while active but I experience a depressive crash when it wears off at the end of the day, higher doses haven't helped. These are stimulants. And an NDRI instead of SSRI. But then I couldn’t go to sleep. Though you could try L-theanine it increases dopamine somewhat. You do not have to get scurvy for Vyvanse to be effective lol. These drugs are often reported to have the opposite effect of the "blunting" from SSRIs - they increase wakefulness, motivation, attention, and sex drive. Start with a Dopamine Detox, then maintain a Dopamine Fast. Effexor and vyvanse aren't hitting norepinephrine too hard, and that's why you got the pounding heartbeat. If you take it with your Vyvanse it helps prolong the affects of the pill a lot also I suggest trying it. Dopaminergic neurotoxicity and dopamine depletion are also concerns: https://pubmed. Before Vyvanse, I was on Strattera, though it gave me intolerable side effects. I have been on Vyvanse for more than a year now and feeling happy/euphoric has never stopped happening for me. Get app Get the Reddit app Log In Log in to Reddit. I usually try to take Enhanced Focus: Vyvanse’s stimulation of dopamine release can lead to improved concentration and attention span. Articles/Information The mobile apps used for Reddit are broken or are missing features that this subreddit depends on. Increased Alertness: The heightened dopamine levels can result in Aug 22, 2024 · One of the most prevalent is the belief that Vyvanse directly increases dopamine levels in the brain, similar to how some other medications work. Down from a about half a pack a day, to 4 ish. I tried Vyvanse from my friend before I recently got prescibed Ritalin to see myself which one worked the best, first I tried 30mg and felt nothing then 60mg and only felt a tiny bit more focused but nothing else. Members Online I feel so sleepy all the time with a ringing sound in the back of my head on detox. Norepinephrine comes along with it and is the “fight or flight” adrenaline response. Has anyone else experienced this? The Hubberman lab talked about this, same with the concept of Dopamine detox. I’m not en expert but I do have reactive hypoglycemia and sugar fixes it lol. This happens in a much smoother way than with other forms of slow-release ADHD meds, so you don't get that rush. I think I've depleted my dopamine or norepinephrine. Thank you! Vyvanse is working too well. The reason cocain can’t be used to treat either of these is because it’s just amplifying the dopamine present, not causing more to be created. 3 months) supplementing of tyrosine, can it deplete serotonin levels, will dopamine levels keep their levels even after quitting the supplement or if quitting it gradually by lowering the Also, wellbutrin is a norepinephrine and dopamine reuptake inhibitor, effexor is a serotonin, and norepinephrine reuptake inhibitor Vyvanse increases the release of dopamine, but also norepinephrine and serotonin. hence the common ‘not lasting long enough’ or ‘not working at all’ even though the substance is still in the system . 30mg makes my muscles so tense and weak that my neck couldn't support my head, I had trouble breathing and swallowing I got switched to concerta. It may very well potentiate dopaminergic stimulants, but all dopamine spikes come at a cost. true. The brain, accustomed to the Dopamine deficiency means having a low level of dopamine. I switched over from Adderall because of the shortage, but my ADHD was well managed on the Adderall when I could get it. And now every single day at 3pm I crave wine. Tyrosine is a pre cursor to dopamine so keeps you topped up and evened out. I think part of the reason this knowledge is so helpful to me personally is the concept of distancing. I take 2mg at night and vyvanse in the morning. Dopamine reuptake inhibitors like Ritalin/Concerta. Vyvanse may last longer than Adderall XR. I’m very attentive to work-related things, tasks needing done around the home, my surroundings, and conversations, but there is a fine line between positive and negative attention with this. More dopamine helps the ADHD brain focus instead of seeking out other low hanging fruit pleasures. This specific crash seems to be caused by depletion of norepinephrine and dopamine. It tails off so gradually that I don’t really even know how long it lasts. Reducing enzymatic breakdown could be seen as reducing the "hole" somewhat. CBD. Understanding the mechanism of action of Vyvanse. I’ve been a vegetarian for over 20 years and I’ve certainly not dieted or considered my diet that closely- wonder how much if any of my dopamine starvation is my own fault. To understand why this isn’t Aug 29, 2023 · What it does is increase the amounts of dopamine in the brain. It's the only way I feel to bring my dopamine back up from the crash. I was W I D E awake until around 6am. I’m in the same boat as you. It's awful. NE without dopamine is a recipe for disaster in most cases because you get all the wired effects of NE without any of the colorful and motivated and effects of dopamine (I'm obviously simplifying but this is the jist of it). I am not really sure about the exact effect that dexamphetamine has and the dopamine system. Or check it out in the app stores Well we were told at pharmacy school that anything long acting working ob dopamine transmission, According to this article too much dopamine depletion prevents 5HTP from being used by the body to rebalance. you may be anhedonic (experience a general lack of pleasure) as well I seriously want a brain transplant. It's a dopamine reuptake inhibitor. does this even happen to people with adhd maybe its dopamine depletion but im not sure about that because apparently people While I am a hairstylist and part time waitress, I didn’t think it was just my job causing this. I do not want to take my Vyvanse everyday if it means that one day, I’ll be unable to focus at ALL without it. CBD partially blocks the dopamine D2 receptor (partial agonist), which has antipsychotic effects . It may or may not work for you, but there is Semax, I personally use it in the form of nasal spray (0,12% concentration, about 160mcg per dose, gotten by buying a 1,0% bottle and using 50ml of bacteriostatic water to reconstitute/dilute it, 2–3 doses per day or less on the days when I can relax and don't feel the need to be productive) for my ADHD and I A support subreddit dedicated to the discussion of Vyvanse (at least for me). Most ADHD meds, or coffee in your case, cause the synthesis of dopamine, along with serotonin and norepinephrine. Dopamine and serotonin are highly regulated and simple neurotransmitters involved in many complex processes, so using something like 5HTP, which the body already makes, should not Vyvanse has helped me a lot in work settings, and I constantly worry about the consequences. Someone who takes Vyvanse for the issues with ADHD is probably already more likely to have Parkinson's. I understand the principles behind slow release and quick release drugs and whatnot, but my question is more concerning dopamine. Prescription drugs known to elevate dopamine are mostly ADHD medication - Ritalin/ Concerta, and Adderall/Vyvanse. I'm trying to make a stack for supporting Vyvanse (30mg) but would appreciate some guidance. Sabroxy doesn't make more of anything, it just increases the amount of time dopamine hangs around outside of neurons. Seems like Doesn't work the same way for Vyvanse as it does Adderall. I did have the dreaded zombie effect on concerta instead of a depression, but only when I went from 36 mg to 54 mg and didn't take enough days off. Amphetamines will be processed out of your system faster the more acidic your urine is, and slower the more alkaline it is, which gets mistranslated into "never consume anything acidic ever or your Vyvanse is useless" when that's absolutely not the case. While studies in mice indicate that 4mg of amphetamine a day for for two weeks resulted in dopamine depletion, that is an incredibly high dose. The response of the body to dopamine reuptake inhibition (methylphenidate, cocaine) is to reduce the amount of the transporters moving dopamine from synapse back to neuron. I remember reading somewhere that a study was done (I believe it was just one professional study/hypothesis) that suggested taking tyrosine with ADHD meds was beneficial and reduces any potential toxicity/over-depletion of natural dopamine reserves/negative impact on dopamine receptors because you are providing your body with exogenous source of dopamine along I'd also like to stress that dopamine depletion could be a huge factor in how you feel. ————————————————— Your body also needs several vitamins and minerals to create dopamine, including iron Personally, I have no experience with methylphenidate. It does FA. Vyvanse, on the other hand, has given me no side effects and is very effective, even though I'm taking a very low dose (20 mg). However, side effects can Dec 26, 2024 · Vyvanse withdrawal can be a challenging experience, especially for those who have relied on the medication for years to manage ADHD or binge eating disorder. My brain was still racing a 1000 miles an hour. Methylphenidate doesn't cause dopamine depletion as easy as amphetamines (Adderall etc). That is to say, tolerance and rebound. I am honored to have my comment appreciated so much, and glad it is seen as helpful by so many people. The effect on vyvanse though was that zombie state mixed with a real deep depression so I figure that maybe my brain can't handle the added dopamine vyvanse gives me or something like that. Or check it out in the app stores Vyvanse, Focalin, Ritalin, etc. Vyvanse was the first stimulant that I tried. I was having panic attacks on 30mg Vyvanse due to the crash. Wellburin, another drug not prescribed for ADHD, also increases dopamine levels. If Vyvanse has stopped working from you ask your doctor to try something else. Interesting. Thank you so much. But if I don’t I get focused on the wrong thing (for example Reddit this morning lol) When I haven’t checked my phone when I wake up and workout/meditate straight away I feel as though I have the motivation to I don't have all the requirements for ADHD but apparently dopamine was what was lacking in my brain and not serotonin (as is usual in depression). One hypothesis The authors hypothesize that schizophrenia is characterized by abnormally low prefrontal dopamine activity (causing deficit symptoms) leading to excessive dopamine activity in mesolimbic dopamine neurons (causing positive symptoms). I talked to my doctor about it and I was told that if these symptoms continue, it would be a good idea to switch to Concerta (Concerta and Vyvanse are the only options in the UK). These directly release and prevent reuptake of dopamine. Hey everyone! I was recently diagnosed with ADHD, so a lot of the medications that are commonly thrown around are still a little fuzzy to me. Yes, decreasing total body acidity will theoretically decrease urinary excretion, but tums is meant to decrease stomach acidity and works better for Adderall. I don’t generally get drunk. This combo has been amazing. Hey bro. The crash is your system basically hemoraging dopamine like a car that runs out of petrol and won't drive any further. Unmedicated, my brain is so hyper I don’t eat anyway. Sometimes masturbating 3 or 4 times a day, having sex dreams most nights, drifting into sexual daydreams. Wondering if low dopamine could be a cause of schizophrenia as well, or if that’s just hogwash. While Aug 22, 2024 · However, this artificial boost in dopamine levels can lead to a phenomenon known as dopamine depletion when the medication is discontinued. gov/9565967/ My heart rate and blood pressure shot up a few years ago (honestly not sure whether it’s due to the Vyvanse or not - I’d never had those issues before, but also they didn’t start until I was like a year into the Vyvanse) and beta blockers didn’t help so my cardiologist recommended Ultra Mag and it worked immediately and has been working for maybe 4ish years now. I'll crave one, light it, and immediately just not want anymore Dopamine based stimulants will deplete your Sodium levels so make sure you're getting enough of your electrolytes; Sodium, Potassium etc. When that happens you have take long breaks like a month or so having really whacked out your already screwed up dopamine levels in order for your meds to help you again. It was great. " If anything, it irritated me because these doctors are being told that Vyvanse is suppose to last 14 hours and Adderall XR is supposed to last 10-12 hours, and I've literally never met anyone that this has been true for. Stimulants and dopamine depletion . (Note: others have said Vyvanse gave them headaches and jittery) Between both pills Vyvanse is a lot more expensive than Adderall XR and there is no generic version for Vyvanse (yet). Us adhders are low of and you’ll start noticing without even taking your Vyvanse. Wondering if I should be pre-emptively taking any other supplements according to what Vyvanse actually Get the Reddit app Scan this QR code to download the app now. I’m on 50 mg of Vyvanse, and my psychiatrist also prescribes me Bupropion. Get the Reddit app Scan this QR code to download the app now. It has basically the opposite effects of antipsychotics. Thanks for asking this! I’ve been wanting to ask for protein shake recommendations myself. I started mainly for help with smoking cessation (2nd times a charm), but I’ve been on it long-term because of it’s antidepressant effects when dealing with a messy divorce, single parenting with an alcoholic ex-spouse, and having my mother move in with my kids and me I’ve also read that l-tyrosine alone helps ADHD. Vyvanse is absorbed best with food as it required cleaving of the lysine attached to the med to work. I've noticed lately that a few of my routine dopamine activities have faded to disinterest. Has i took Vyvanse at 8:55am and fell asleep till 11:00am and was feeling r/ADHD A chip A close button. Going off the vyvanse without a substitute is an option, depending mostly of why you were prescribed it in the first place. As we know, with ADHD the DRD2 gene, the one thats defected for us makes it difficult for neurons to respond to dopamine. Im looking for someone to explain what could be the outcome of longterm (eg. The right amount of dopamine allows the prefrontal cortex to work properly and we should have the ability to control and shift focus. Are you curious about the effects of Vyvanse on one of the brain’s most crucial neurotransmitters, dopamine? Dive into this in-depth exploration of Vyvanse and its potential influence on dopamine levels. Since the drugs that act in dopamine mostly target different sets of receptors either supplementation or switching to a different pill would have a good chance of fixing the problem. I did so much research online, went through many Reddit threads, asked my doc what supplements they recommend, etc. I don’t want to say the wrong info but I guess vyvanse and abilify work on different dopamine receptors. But, ever since starting on Vyvanse I am like, insatiably horny. Vyvanse helps my short term motivation, but not necessarily my long term motivation (which is required to stick with those creative pursuits and hobbies that require time to perfect). Vyvanse is a chemical which metabolises into dextroamphetamine once in the body. ) and topics directly related to them. I got put on adderall and vyvanse when I was 15 and I’m 21 now and just getting off it. Maybe Adderall or Ritalin would work better. Like dexmethylphenidate, it acts as a norepinephrine and dopamine reuptake inhibitor but with a less targeted action than the more potent d-enantiomer found in Focalin. Morning: Breakfast with; 1x Omega-3 Fish Oil Triple Strength 1000mg (Nootropics Depot) I'm not sure that therapeutic dosages of amphetamines cause dopamine neuron depletion in humans. Ritalin is a DRI which may be a little more equilibrium based than Adderall/Vyvanse since it's not actually causing more dopamine to be released. However, from what I can understand of the Wikipedia page it releases dopamine (and other neurotransmitters) and also reduces enzymatic breakdown of these. So the idea is to support the nutrient depletion, but also to support cognition and memory function (my biggest symptomatic problem) in general. The euphoria comes from too much dopamine being released at once, and that depends on how fast the amphetamine enters the brain. I feel more joyful on Vyvanse than I ever did on Adderall. I went off Vyvanse after about 2 years on 40mg, and that definitely wasn't the case for me. pehnlt dtsjbldk rpz wrdauj tywpgn izayo zgzfse krbm ult lrs esiyy myc wbn ebwed tagwt